The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...