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» Mining biological networks for unknown pathways
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EMO
2005
Springer
108views Optimization» more  EMO 2005»
13 years 11 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 24 days ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
BICOB
2010
Springer
13 years 6 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
RECOMB
2007
Springer
14 years 6 months ago
QNet: A Tool for Querying Protein Interaction Networks
Molecular interaction databases can be used to study the evolution of molecular pathways across species. Querying such pathways is a challenging computational problem, and recent e...
Banu Dost, Tomer Shlomi, Nitin Gupta 0002, Eytan R...
IJCNN
2006
IEEE
14 years 7 days ago
Reconstruction of Gene Regulatory Networks from Temporal Microarray Data Using Pattern Recognition Techniques
- Gene regulatory networks allow us to study and understand genes’ roles in biological processes. Among others, regulatory networks help to identify pathway initiator genes and t...
Azhar Salim, Faramarz Valafar