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» Mining biological networks for unknown pathways
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BMCBI
2006
114views more  BMCBI 2006»
13 years 6 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
13 years 11 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2007
165views more  BMCBI 2007»
13 years 6 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
BMCBI
2006
166views more  BMCBI 2006»
13 years 6 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
SDM
2009
SIAM
162views Data Mining» more  SDM 2009»
14 years 3 months ago
Link Propagation: A Fast Semi-supervised Learning Algorithm for Link Prediction.
We propose Link Propagation as a new semi-supervised learning method for link prediction problems, where the task is to predict unknown parts of the network structure by using aux...
Hisashi Kashima, Tsuyoshi Kato, Yoshihiro Yamanish...