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» Mining protein networks for synthetic genetic interactions
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BIOCOMP
2006
14 years 11 months ago
Learning Genetic and Gene Bayesian Networks with Hidden Variables: Bilayer Verification Algorithm
To improve the recovery of gene-gene and marker-gene (eQTL) interaction networks from microarray and genetic data, we propose a new procedure for learning Bayesian networks. This a...
Jason E. Aten
BMCBI
2007
168views more  BMCBI 2007»
14 years 9 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
RECOMB
2007
Springer
15 years 9 months ago
QNet: A Tool for Querying Protein Interaction Networks
Molecular interaction databases can be used to study the evolution of molecular pathways across species. Querying such pathways is a challenging computational problem, and recent e...
Banu Dost, Tomer Shlomi, Nitin Gupta 0002, Eytan R...
87
Voted
GPEM
2007
119views more  GPEM 2007»
14 years 9 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
80
Voted
BMCBI
2008
120views more  BMCBI 2008»
14 years 9 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...