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» Model Based Analysis of Signaling Pathways
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BMCBI
2006
117views more  BMCBI 2006»
14 years 10 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
ISQED
2007
IEEE
151views Hardware» more  ISQED 2007»
15 years 4 months ago
Gate Level Statistical Simulation Based on Parameterized Models for Process and Signal Variations
We propose gate level statistical simulation to bridge the gap between the most accurate Monte Carlo SPICE simulation and the most efficient circuit level statistical static timi...
Bao Liu
ICPR
2002
IEEE
15 years 11 months ago
Fractional Component Analysis (FCA) for Mixed Signals
This paper proposes the fractional component analysis (FCA), whose goal is to decompose the observed signal into component signals and recover their fractions. The uniqueness of o...
Asanobu Kitamoto
BMCBI
2010
100views more  BMCBI 2010»
14 years 10 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2006
133views more  BMCBI 2006»
14 years 10 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...