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» Model Based Analysis of Signaling Pathways
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BMCBI
2011
14 years 1 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
JMLR
2010
105views more  JMLR 2010»
14 years 4 months ago
Evaluation of Signaling Cascades Based on the Weights from Microarray and ChIP-seq Data
In this study, we combined the ChIP-seq and the transcriptome data and integrated these data into signaling cascades. Integration was realized through a framework based on data- a...
Zerrin Isik, Volkan Atalay, Rengül Çet...
AVSS
2009
IEEE
15 years 3 months ago
Segment Model Based Vehicle Motion Analysis
Pengfei Zhu, Weiming Hu, Xi Li, Li Li
BMCBI
2010
150views more  BMCBI 2010»
14 years 10 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
APN
2006
Springer
14 years 12 months ago
From Petri Nets to Differential Equations - An Integrative Approach for Biochemical Network Analysis
Abstract. We report on the results of an investigation into the integration of Petri nets and ordinary differential equations (ODEs) for the modelling and analysis of biochemical n...
David Gilbert, Monika Heiner