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» Model Based Analysis of Signaling Pathways
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APLAS
2007
ACM
15 years 2 months ago
Scalable Simulation of Cellular Signaling Networks
Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
Vincent Danos, Jérôme Feret, Walter F...
BC
2008
73views more  BC 2008»
14 years 10 months ago
Interaction of ON and OFF pathways for visual contrast measurement
We propose a novel model of visual contrast measurement based on segregated ON and OFF pathways. Two driving forces have shaped our investigation: (1) establishing a mechanism sele...
Heiko Neumann, Luiz Pessoa, Thorsten Hansen
BMCBI
2010
130views more  BMCBI 2010»
14 years 10 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
RECOMB
2001
Springer
15 years 2 months ago
Extracting structural information using time-frequency analysis of protein NMR data
High-throughput, data-directed computational protocols for Structural Genomics (or Proteomics) are required in order to evaluate the protein products of genes for structure and fu...
Christopher James Langmead, Bruce Randall Donald
DATE
2008
IEEE
125views Hardware» more  DATE 2008»
15 years 4 months ago
Current source based standard cell model for accurate signal integrity and timing analysis
— The inductance and coupling effects in interconnects and non-linear receiver loads has resulted in complex input signals and output loads for gates in the modern deep submicron...
Amit Goel, Sarma B. K. Vrudhula