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103
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BMCBI
2006
239views more  BMCBI 2006»
15 years 15 days ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
93
Voted
BMCBI
2006
82views more  BMCBI 2006»
15 years 15 days ago
Transcriptomic response to differentiation induction
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...
BMCBI
2006
137views more  BMCBI 2006»
15 years 15 days ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
HEURISTICS
2008
124views more  HEURISTICS 2008»
15 years 15 days ago
A variable neighborhood search for the capacitated arc routing problem with intermediate facilities
In this talk we present a unified Variable Neighborhood Search (VNS) algorithm for the Capacitated Arc Routing Problem (CARP) and some of its variants - the Capacitated Arc Routin...
Michael Polacek, Karl F. Doerner, Richard F. Hartl...
119
Voted
BMCBI
2006
161views more  BMCBI 2006»
15 years 15 days ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
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