A legacy system is an operational, large-scale software system that is maintained beyond its first generation of programmers. It typically represents a massive economic investmen...
Kostas Kontogiannis, Renato de Mori, Morris Bernst...
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
Omniscient debuggers make it possible to navigate backwards in time within a program execution trace, drastically improving the task of debugging complex applications. Still, they...
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...