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BMCBI
2008
114views more  BMCBI 2008»
15 years 3 months ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
JIB
2007
95views more  JIB 2007»
15 years 3 months ago
Integration of constraints documented in SBML, SBO, and the SBML Manual facilitates validation of biological models
The creation of quantitative, simulatable, Systems Biology Markup Language (SBML) models that accurately simulate the system under study is a time-intensive manual process that re...
Allyson L. Lister, Matthew R. Pocock, Anil Wipat
CBMS
2007
IEEE
15 years 9 months ago
Ontology Engineering to Model Clinical Pathways: Towards the Computerization and Execution of Clinical Pathways
Clinical pathways translate evidence-based recommendations into locally practicable, process-specific algorithms that reduce practice variations and optimize quality of care. Our ...
Katrina F. Hurley, Syed Sibte Raza Abidi
IDEAS
2009
IEEE
232views Database» more  IDEAS 2009»
15 years 9 months ago
RDFKB: efficient support for RDF inference queries and knowledge management
RDFKB (Resource Description Framework Knowledge Base) is a relational database system for RDF datasets which supports inference and knowledge management. Significant research has ...
James P. McGlothlin, Latifur R. Khan
DESRIST
2009
Springer
143views Education» more  DESRIST 2009»
15 years 7 months ago
Designing for complex innovations in health care: design theory and realist evaluation combined
Innovations in health care are often characterized by complexity and fuzzy boundaries, involving both the elements of the innovation and the organizational structure required for ...
Christina Keller, Klas Gäre, Mats Edenius, St...