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BMCBI
2004
87views more  BMCBI 2004»
14 years 9 months ago
prot4EST: Translating Expressed Sequence Tags from neglected genomes
Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
James Wasmuth, Mark L. Blaxter
PRL
2006
130views more  PRL 2006»
14 years 9 months ago
Efficient huge-scale feature selection with speciated genetic algorithm
With increasing interest in bioinformatics, sophisticated tools are required to efficiently analyze gene information. The classification of gene expression profiles is crucial in ...
Jin-Hyuk Hong, Sung-Bae Cho
BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
15 years 4 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
93
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BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
BMCBI
2010
164views more  BMCBI 2010»
14 years 7 months ago
Merged consensus clustering to assess and improve class discovery with microarray data
Background: One of the most commonly performed tasks when analysing high throughput gene expression data is to use clustering methods to classify the data into groups. There are a...
T. Ian Simpson, J. Douglas Armstrong, Andrew P. Ja...