Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
Brian D. M. Tom, Walter R. Gilks, Elizabeth T. Bro...
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
Background: During the past decade, many software packages have been developed for analysis and visualization of various types of microarrays. We have developed and maintained the...