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BMCBI
2007
186views more  BMCBI 2007»
14 years 9 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2008
155views more  BMCBI 2008»
14 years 9 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
JCST
2008
124views more  JCST 2008»
14 years 9 months ago
Clustering by Pattern Similarity
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Haixun Wang, Jian Pei
BMCBI
2010
178views more  BMCBI 2010»
14 years 9 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...