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GFKL
2005
Springer
141views Data Mining» more  GFKL 2005»
15 years 3 months ago
On External Indices for Mixtures: Validating Mixtures of Genes
Mixture models represent results of gene expression cluster analysis in a more natural way than ’hard’ partitions. This is also true for the representation of gene labels, such...
Ivan G. Costa, Alexander Schliep
IDA
2003
Springer
15 years 2 months ago
An Iterated Local Search Approach for Minimum Sum-of-Squares Clustering
Abstract. Since minimum sum-of-squares clustering (MSSC) is an NPhard combinatorial optimization problem, applying techniques from global optimization appears to be promising for r...
Peter Merz
BMCBI
2010
152views more  BMCBI 2010»
14 years 9 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
BMCBI
2005
112views more  BMCBI 2005»
14 years 9 months ago
"Harshlighting" small blemishes on microarrays
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Asifa Haider, ...
TCBB
2011
14 years 4 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...