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GCB
2005
Springer
138views Biometrics» more  GCB 2005»
15 years 9 months ago
Inferring Regulatory Systems with Noisy Pathway Information
: With increasing number of pathways available in public databases, the process of inferring gene regulatory networks becomes more and more feasible. The major problem of most of t...
Christian Spieth, Felix Streichert, Nora Speer, An...
FUZZIEEE
2007
IEEE
15 years 10 months ago
A Feature Selection Method Based on Choquet Integral and Typicality Analysis
— An iterative feature selection method based on feature typicality and interactivity analysis is presented in this paper. The aim is to enhance model interpretability by selecti...
Cyril Mazaud, Jan Rendek, Vincent Bombardier, Laur...
BMCBI
2006
239views more  BMCBI 2006»
15 years 4 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
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BMCBI
2004
115views more  BMCBI 2004»
15 years 4 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BMCBI
2004
146views more  BMCBI 2004»
15 years 4 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker