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ISVC
2007
Springer
15 years 8 months ago
Integrative Geometric-Hashing Approaches to Binding Site Modeling and Ligand-Protein Interaction Prediction
Abstract. The function of a protein is dependent on whether and how it can interact with various ligands. Therefore, an accurate prediction of protein-ligand interactions is paramo...
Joanna Lipinski-Kruszka, Rahul Singh
TELETRAFFIC
2007
Springer
15 years 8 months ago
Modeling and Predicting End-to-End Response Times in Multi-tier Internet Applications
Many Internet applications employ multi-tier software architectures. The performance of such multi-tier Internet applications is typically measured by the end-toend response times...
Sandjai Bhulai, Swaminathan Sivasubramanian, Rober...
BIBM
2010
IEEE
139views Bioinformatics» more  BIBM 2010»
14 years 11 months ago
Scalable, updatable predictive models for sequence data
The emergence of data rich domains has led to an exponential growth in the size and number of data repositories, offering exciting opportunities to learn from the data using machin...
Neeraj Koul, Ngot Bui, Vasant Honavar
BMCBI
2010
120views more  BMCBI 2010»
15 years 2 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BMCBI
2006
159views more  BMCBI 2006»
15 years 2 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey