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BMCBI
2010
146views more  BMCBI 2010»
14 years 9 months ago
A pairwise residue contact area-based mean force potential for discrimination of native protein structure
Background: Considering energy function to detect a correct protein fold from incorrect ones is very important for protein structure prediction and protein folding. Knowledge-base...
Shahriar Arab, Mehdi Sadeghi, Changiz Eslahchi, Ha...
IJCBDD
2010
127views more  IJCBDD 2010»
14 years 8 months ago
Predicting protein complexes by data integration of different types of interactions
: The explosion of highthroughput interaction data from proteomics studies gives us the opportunity to integrate Protein-Protein Interactions (PPI) from different type of interacti...
Powell Patrick Cheng Tan, Daryanaz Dargahi, Freder...
BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2008
138views more  BMCBI 2008»
14 years 9 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
ISMB
1996
14 years 11 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli