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BMCBI
2008
169views more  BMCBI 2008»
15 years 1 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...
BMCBI
2007
148views more  BMCBI 2007»
15 years 1 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
VEE
2012
ACM
187views Virtualization» more  VEE 2012»
13 years 9 months ago
DDGacc: boosting dynamic DDG-based binary optimizations through specialized hardware support
Dynamic Binary Translators (DBT) and Dynamic Binary Optimization (DBO) by software are used widely for several reasons including performance, design simplification and virtualiza...
Demos Pavlou, Enric Gibert, Fernando Latorre, Anto...
ASPLOS
2009
ACM
16 years 2 months ago
RapidMRC: approximating L2 miss rate curves on commodity systems for online optimizations
Miss rate curves (MRCs) are useful in a number of contexts. In our research, online L2 cache MRCs enable us to dynamically identify optimal cache sizes when cache-partitioning a s...
David K. Tam, Reza Azimi, Livio Soares, Michael St...
STOC
2006
ACM
129views Algorithms» more  STOC 2006»
16 years 1 months ago
Optimal phylogenetic reconstruction
One of the major tasks of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on the true evolu...
Constantinos Daskalakis, Elchanan Mossel, Sé...
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