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BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMEI
2009
IEEE
14 years 10 months ago
A Kurtosis and Skewness Based Criterion for Model Selection on Gaussian Mixture
The Gaussian mixture model is a powerful statistical tool in data modeling and analysis. Generally, the EM algorithm is utilized to learn the parameters of the Gaussian mixture. Ho...
Lin Wang, Jinwen Ma
GECCO
2007
Springer
154views Optimization» more  GECCO 2007»
15 years 3 months ago
A novel ab-initio genetic-based approach for protein folding prediction
In this paper, a model based on genetic algorithms for protein folding prediction is proposed. The most important features of the proposed approach are: i) Heuristic secondary str...
Sergio Raul Duarte Torres, David Camilo Becerra Ro...
GECCO
2006
Springer
180views Optimization» more  GECCO 2006»
15 years 1 months ago
Improving cooperative GP ensemble with clustering and pruning for pattern classification
A boosting algorithm based on cellular genetic programming to build an ensemble of predictors is proposed. The method evolves a population of trees for a fixed number of rounds an...
Gianluigi Folino, Clara Pizzuti, Giandomenico Spez...
TEC
2002
133views more  TEC 2002»
14 years 9 months ago
Learning and optimization using the clonal selection principle
The clonal selection principle is used to explain the basic features of an adaptive immune response to an antigenic stimulus. It establishes the idea that only those cells that rec...
Leandro Nunes de Castro, Fernando J. Von Zuben