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141
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BMCBI
2008
138views more  BMCBI 2008»
15 years 3 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
120
Voted
BMCBI
2006
131views more  BMCBI 2006»
15 years 3 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
148
Voted
BMCBI
2006
125views more  BMCBI 2006»
15 years 3 months ago
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
Hiraku Morisawa, Mikako Hirota, Tosifusa Toda
113
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TCBB
2008
93views more  TCBB 2008»
15 years 3 months ago
2SNP: Scalable Phasing Method for Trios and Unrelated Individuals
Emerging microarray technologies allow affordable typing of very long genome sequences. A key challenge in analyzing of such huge amount of data is scalable and accurate computatio...
Dumitru Brinza, Alexander Zelikovsky
136
Voted
BMCBI
2005
104views more  BMCBI 2005»
15 years 3 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
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