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HPDC
2010
IEEE
14 years 11 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
BMCBI
2010
131views more  BMCBI 2010»
14 years 10 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
114
Voted
BMCBI
2005
198views more  BMCBI 2005»
14 years 10 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
86
Voted
BMCBI
2006
144views more  BMCBI 2006»
14 years 10 months ago
ProFAT: a web-based tool for the functional annotation of protein sequences
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
77
Voted
BIBE
2010
IEEE
144views Bioinformatics» more  BIBE 2010»
14 years 11 months ago
Detecting Coevolution of Functionally Related Proteins for Automated Protein Annotation
Alan L. Kwan, Susan K. Dutcher, Gary D. Stormo