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CIBB
2009
15 years 7 months ago
On the Use of Temporal Formal Logic to Model Gene Regulatory Networks
Modelling activities in molecular biology face the difficulty of prediction to link molecular knowledge with cell phenotypes. Even when the interaction graph between molecules is k...
Gilles Bernot, Jean-Paul Comet
IJON
2007
73views more  IJON 2007»
15 years 6 months ago
A biophysical model of short-term plasticity at the calyx of Held
The calyx of Held is a giant glutamatergic synapse in the auditory system and displays multiple forms of short-term facilitation and depression. This study presents a detailed mod...
Matthias H. Hennig, Michael Postlethwaite, Ian D. ...
IFM
2010
Springer
204views Formal Methods» more  IFM 2010»
15 years 4 months ago
Collaborative Modelling and Co-simulation in the Development of Dependable Embedded Systems
This paper presents initial results of research aimed at developing methods and tools for multidisciplinary collaborative development of dependable embedded systems. We focus on th...
John S. Fitzgerald, Peter Gorm Larsen, Ken Pierce,...
ENTCS
2010
103views more  ENTCS 2010»
15 years 3 months ago
A Model and Analysis of the AKAP Scaffold
We study the biochemical processes involved in scaffold-mediated crosstalk between the cAMP and the Raf-1/MEK/ERK pathways. We model the system by a continuous time Markov chain w...
Oana Andrei, Muffy Calder
173
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IJDMB
2011
129views more  IJDMB 2011»
14 years 9 months ago
Modelling gene and protein regulatory networks with Answer Set Programming
: Recently, many approaches to model regulatory networks have been proposed in the systems biology domain, however the task is far from being solved. In this paper we propose an an...
Timur Fayruzov, Jeroen Janssen, Dirk Vermeir, Chri...