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» Modelling Gene Regulatory Networks
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IDA
2009
Springer
14 years 7 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
CEC
2003
IEEE
15 years 1 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
CEC
2008
IEEE
14 years 10 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
ALIFE
2005
14 years 9 months ago
A Gene Network Model for Developing Cell Lineages
Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains sufficient information to generate a variety of differentiated cell ...
Nicholas Geard, Janet Wiles