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» Modelling Gene Regulatory Networks
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RECOMB
2005
Springer
15 years 10 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
APBC
2004
116views Bioinformatics» more  APBC 2004»
14 years 11 months ago
Evolving Genetic Regulatory Networks Using an Artificial Genome
Boolean models of genetic regulatory networks (GRNs) have been shown to exhibit many of the characteristic dynamics of real GRNs, with gene expression patterns settling to point a...
Jennifer Hallinan, Janet Wiles
ENTCS
2007
96views more  ENTCS 2007»
14 years 9 months ago
Semantics of Biological Regulatory Networks
The aim of the paper is to revisit the model of Biological Regulatory Networks (BRN) which was proposed by René Thomas to model the interactions between a set of genes. We give a...
Gilles Bernot, Franck Cassez, Jean-Paul Comet, Fra...
CIBCB
2009
IEEE
14 years 11 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty
BMCBI
2007
146views more  BMCBI 2007»
14 years 10 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...