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» Modelling Gene Regulatory Networks
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JMLR
2012
13 years 10 days ago
Bayesian regularization of non-homogeneous dynamic Bayesian networks by globally coupling interaction parameters
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Marco Grzegorczyk, Dirk Husmeier
IJBRA
2008
101views more  IJBRA 2008»
14 years 10 months ago
Analysing formal models of genetic regulatory networks with delays
: In this paper, we propose a refinement of the modelling of biological regulatory networks based on the discrete approach of Ren
Jamil Ahmad, Olivier Roux, Gilles Bernot, Jean-Pau...
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
15 years 3 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
BMCBI
2010
100views more  BMCBI 2010»
14 years 10 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao