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» Modelling Gene Regulatory Networks
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CGF
2008
142views more  CGF 2008»
14 years 10 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
BMCBI
2007
114views more  BMCBI 2007»
14 years 10 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
JCB
2008
170views more  JCB 2008»
14 years 10 months ago
Efficiently Identifying Max-Gap Clusters in Pairwise Genome Comparison
The spatial clustering of genes across different genomes has been used to study important problems in comparative genomics, from identification of operons to detection of homologo...
Xu Ling, Xin He, Dong Xin, Jiawei Han
ICML
2009
IEEE
15 years 10 months ago
Dynamic mixed membership blockmodel for evolving networks
In a dynamic social or biological environment, interactions between the underlying actors can undergo large and systematic changes. Each actor can assume multiple roles and their ...
Wenjie Fu, Le Song, Eric P. Xing
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
15 years 4 months ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke