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» Modelling Gene Regulatory Networks
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IPPS
2003
IEEE
15 years 3 months ago
Parallel Detection of Regulatory Elements with gMP
The detection of regulatory elements from a large set of regulatory regions is a challenging problem in computational genomics. However, computational methods to extract this biol...
Bertil Schmidt, Lin Feng, Amey V. Laud, Yusdi Sant...
RECOMB
2004
Springer
15 years 10 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
BMCBI
2010
97views more  BMCBI 2010»
14 years 10 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
RECOMB
2005
Springer
15 years 10 months ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola
FMCAD
2007
Springer
15 years 4 months ago
Analyzing Gene Relationships for Down Syndrome with Labeled Transition Graphs
Abstract— The relationship between changes in gene expression and physical characteristics associated with Down syndrome is not well understood. Chromosome 21 genes interact with...
Neha Rungta, Hyrum Carroll, Eric G. Mercer, Randal...