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» Modelling Gene Regulatory Networks
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RECOMB
2003
Springer
15 years 10 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
ISMB
1997
14 years 11 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
BMCBI
2007
122views more  BMCBI 2007»
14 years 10 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
CIBCB
2009
IEEE
14 years 7 months ago
An automatic gene ontology software tool for bicluster and cluster comparisons
We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster...
Fadhl M. Al-Akwaa, Yasser M. Kadah
BMCBI
2010
240views more  BMCBI 2010»
14 years 10 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...