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» Modelling Gene Regulatory Networks
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BMCBI
2006
136views more  BMCBI 2006»
14 years 10 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
BMCBI
2008
100views more  BMCBI 2008»
14 years 10 months ago
Extracting transcription factor binding sites from unaligned gene sequences with statistical models
Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hyb...
Chung-Chin Lu, Wei-Hao Yuan, Te-Ming Chen
CMSB
2006
Springer
15 years 1 months ago
Compositional Reachability Analysis of Genetic Networks
Genetic regulatory networks have been modeled as discrete transition systems by many approaches, benefiting from a large number of formal verification algorithms available for the ...
Gregor Gößler
BMCBI
2010
115views more  BMCBI 2010»
14 years 10 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMEI
2008
IEEE
15 years 4 months ago
Using Phylogenetic Relationships to Improve the Inference of Transcriptional Regulatory Networks
Inferring transcriptional regulatory networks from geneexpression data remains a challenging problem, in part because of the noisy nature of the data and the lack of strong networ...
Xiuwei Zhang, Maryam Zaheri, Bernard M. E. Moret