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» Modelling Gene Regulatory Networks
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BMCBI
2008
135views more  BMCBI 2008»
14 years 10 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
14 years 10 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...
BMCBI
2010
165views more  BMCBI 2010»
14 years 10 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
FUIN
2007
109views more  FUIN 2007»
14 years 10 months ago
Unifying Framework for Rule Semantics: Application to Gene Expression Data
Abstract. The notion of rules is very popular and appears in different flavors, for example as association rules in data mining or as functional dependencies in databases. Their s...
Marie Agier, Jean-Marc Petit, Einoshin Suzuki
BMCBI
2004
185views more  BMCBI 2004»
14 years 9 months ago
Linear fuzzy gene network models obtained from microarray data by exhaustive search
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
Bahrad A. Sokhansanj, J. Patrick Fitch, Judy N. Qu...