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» Modelling Gene Regulatory Networks
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EVOW
2010
Springer
14 years 8 months ago
Finding Gapped Motifs by a Novel Evolutionary Algorithm
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Chengwei Lei, Jianhua Ruan
BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
IJDMB
2008
105views more  IJDMB 2008»
14 years 10 months ago
Temporal representation for gene networks: towards a qualitative temporal data mining
: Recently lots of studies aim at modeling and inferring gene networks. Modeling tools propose graphical models having almost nothing about time description of events and regards t...
Nicolas Turenne, Sylviane R. Schwer
BMCBI
2007
141views more  BMCBI 2007»
14 years 10 months ago
On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia c...
Marco Fondi, Matteo Brilli, Renato Fani
SAC
2004
ACM
15 years 3 months ago
Time-frequency feature detection for time-course microarray data
Gene clustering based on microarray data provides useful functional information to the working biologists. Many current gene-clustering algorithms rely on Euclidean-based distance...
Jiawu Feng, Paolo Emilio Barbano, Bud Mishra