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» Modelling Gene Regulatory Networks
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NAR
2002
141views more  NAR 2002»
14 years 9 months ago
Co-expression pattern from DNA microarray experiments as a tool for operon prediction
The prediction of operons, the smallest unit of transcription in prokaryotes, is the first step towards reconstruction of a regulatory network at the whole genome level. Sequence ...
Chiara Sabatti, Lars Rohlin, Min-Kyu Oh, James C. ...
FM
2009
Springer
138views Formal Methods» more  FM 2009»
15 years 4 months ago
What Can Formal Methods Bring to Systems Biology?
This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...
AIME
2005
Springer
14 years 12 months ago
An Algorithm to Learn Causal Relations Between Genes from Steady State Data: Simulation and Its Application to Melanoma Dataset
In recent years, a few researchers have challenged past dogma and suggested methods (such as the IC algorithm) for inferring causal relationship among variables using steady state ...
Xin Zhang, Chitta Baral, Seungchan Kim
ISMIS
2005
Springer
15 years 3 months ago
Towards Ad-Hoc Rule Semantics for Gene Expression Data
The notion of rules is very popular and appears in different flavors, for example as association rules in data mining or as functional (or multivalued) dependencies in databases. ...
Marie Agier, Jean-Marc Petit, Einoshin Suzuki
APBC
2004
122views Bioinformatics» more  APBC 2004»
14 years 11 months ago
Integrating Biopathway Databases for Large-scale Modeling and Simulation
Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathw...
Masao Nagasaki, Atsushi Doi, Hiroshi Matsuno, Sato...