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» Modelling Gene Regulatory Networks
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RECOMB
2000
Springer
15 years 1 months ago
Using Bayesian networks to analyze expression data
DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a "snapshot" of transcription levels within the c...
Nir Friedman, Michal Linial, Iftach Nachman, Dana ...
IJBRA
2006
59views more  IJBRA 2006»
14 years 10 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
ECAL
2005
Springer
15 years 3 months ago
CelloS: A Multi-level Approach to Evolutionary Dynamics
We study the evolution of simple cells that are equipped with a genome, a rudimentary gene regulation network at transcription level and two classes of functional genes: motion eï¬...
Camille Stephan-Otto Attolini, Peter F. Stadler, C...
BMCBI
2007
137views more  BMCBI 2007»
14 years 10 months ago
PlnTFDB: an integrative plant transcription factor database
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Diego Mauricio Riaño-Pachón, Sloboda...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...