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BIODATAMINING
2008
117views more  BIODATAMINING 2008»
14 years 12 months ago
Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database
Background: In computer science, database systems are based on the relational model founded by Edgar Codd in 1970. On the other hand, in the area of biology the word 'databas...
Masanori Arita, Kazuhiro Suwa
BIOINFORMATICS
2007
151views more  BIOINFORMATICS 2007»
14 years 12 months ago
A new protein-protein docking scoring function based on interface residue properties
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Julie Bernauer, Jérôme Azé, Jo...
BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...
BMCBI
2010
92views more  BMCBI 2010»
14 years 12 months ago
YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast
Background: The budding yeast Saccharomyces cerevisiae is one of the most widely studied model organisms in aging-related science. Although several genetic modifiers of yeast long...
Brady Olsen, Christopher J. Murakami, Matt Kaeberl...
BMCBI
2010
105views more  BMCBI 2010»
14 years 12 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
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