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BMCBI
2007
141views more  BMCBI 2007»
13 years 6 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2010
133views more  BMCBI 2010»
13 years 6 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2010
165views more  BMCBI 2010»
13 years 6 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2010
176views more  BMCBI 2010»
13 years 6 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
ICDM
2010
IEEE
186views Data Mining» more  ICDM 2010»
13 years 4 months ago
MoodCast: Emotion Prediction via Dynamic Continuous Factor Graph Model
Human emotion is one important underlying force affecting and affected by the dynamics of social networks. An interesting question is "can we predict a person's mood base...
Yuan Zhang, Jie Tang, Jimeng Sun, Yiran Chen, Jing...