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» Models and Methods in Comparative Genomics
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162
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JCB
2007
145views more  JCB 2007»
15 years 3 months ago
Confounding Factors in HGT Detection: Statistical Error, Coalescent Effects, and Multiple Solutions
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). This process has great significance for unde...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
144
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GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
15 years 9 months ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
132
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BMCBI
2010
87views more  BMCBI 2010»
15 years 3 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
151
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IJCNLP
2004
Springer
15 years 9 months ago
Window-Based Method for Information Retrieval
In this paper, a series of window-based methods is proposed for information retrieval. Compared with traditional tf-idf model, our approaches are based on two new key notions. The ...
Qianli Jin, Jun Zhao, Bo Xu
138
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BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan