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135
Voted
BMCBI
2005
15 years 3 months ago
2005
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
144
Voted
ICPR
2006
IEEE
16 years 4 months ago
2006
IEEE
It is possible to broadly characterize two approaches to probabilistic modeling in terms of generative and discriminative methods. Provided with sufficient training data the discr...
168
Voted
BMCBI
2005
15 years 3 months ago
2005
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
175
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BMCBI
2008
15 years 3 months ago
2008
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
133
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JCB
2006
15 years 3 months ago
2006
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...