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» Models and Methods in Comparative Genomics
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JCB
2007
191views more  JCB 2007»
14 years 9 months ago
Bayesian Haplotype Inference via the Dirichlet Process
The problem of inferring haplotypes from genotypes of single nucleotide polymorphisms (SNPs) is essential for the understanding of genetic variation within and among populations, ...
Eric P. Xing, Michael I. Jordan, Roded Sharan
RECOMB
2003
Springer
15 years 10 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
RECOMB
2008
Springer
15 years 10 months ago
Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evo
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
ISMB
2007
15 years 4 days ago
Automatic genome-wide reconstruction of phylogenetic gene trees
Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...