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» Models and Methods in Comparative Genomics
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RECOMB
2007
Springer
15 years 10 months ago
A Bayesian Model That Links Microarray mRNA Measurements to Mass Spectrometry Protein Measurements
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Anitha Kannan, Andrew Emili, Brendan J. Frey
BMCBI
2006
122views more  BMCBI 2006»
14 years 10 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
KDD
2005
ACM
130views Data Mining» more  KDD 2005»
15 years 10 months ago
Simple and effective visual models for gene expression cancer diagnostics
In the paper we show that diagnostic classes in cancer gene expression data sets, which most often include thousands of features (genes), may be effectively separated with simple ...
Gregor Leban, Minca Mramor, Ivan Bratko, Blaz Zupa...
BMCBI
2010
129views more  BMCBI 2010»
14 years 10 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini