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» Models and Methods in Comparative Genomics
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107
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BMCBI
2010
89views more  BMCBI 2010»
15 years 3 months ago
Detection of gene pathways with predictive power for breast cancer prognosis
Background: Prognosis is of critical interest in breast cancer research. Biomedical studies suggest that genomic measurements may have independent predictive power for prognosis. ...
Shuangge Ma, Michael R. Kosorok
146
Voted
BMCBI
2006
116views more  BMCBI 2006»
15 years 3 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
147
Voted
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
15 years 1 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
117
Voted
TSMC
2002
112views more  TSMC 2002»
15 years 3 months ago
A method for evaluating elicitation schemes for probabilistic models
We present an objective approach for evaluating probability and structure elicitation methods in probabilistic models. The main idea is to use the model derived from the experts�...
Haiqin Wang, Denver Dash, Marek J. Druzdzel
151
Voted
CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
15 years 8 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision