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» Models and Methods in Comparative Genomics
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120
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BMCBI
2008
93views more  BMCBI 2008»
15 years 3 months ago
Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Guillaume Launay, Thomas Simonson
134
Voted
BMCBI
2008
171views more  BMCBI 2008»
15 years 3 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
160
Voted
WSC
1997
15 years 4 months ago
Structured Models and Dynamic Systems Analysis: The Integration of the IDEF0/IDEF3 Modeling Methods and Discrete Event Simulatio
The role of modeling and simulation is receiving much press of late. However, the lack of practice in employing a link between the two is alarming. A static model is used to under...
Larry Whitman, Brian L. Huff, Adrien Presley
109
Voted
IMECS
2007
15 years 5 months ago
Pseudo-Reverse Approach in Genetic Evolution: An Empirical Study with Enzymes
— A pseudo-reverse approach is presented in this paper to analyze the evolutionary behaviour of enzymes. It employs the standard model of Nei and Gojobori [1] in a generalized fo...
Sukanya Manna, Cheng-Yuan Liou
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
15 years 10 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...