Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
The role of modeling and simulation is receiving much press of late. However, the lack of practice in employing a link between the two is alarming. A static model is used to under...
— A pseudo-reverse approach is presented in this paper to analyze the evolutionary behaviour of enzymes. It employs the standard model of Nei and Gojobori [1] in a generalized fo...
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...