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» Models and Methods in Comparative Genomics
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BMCBI
2007
135views more  BMCBI 2007»
15 years 3 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
ICASSP
2007
IEEE
15 years 9 months ago
Wavelet Footprints and Sparse Bayesian Learning for DNA Copy Number Change Analysis
Alterations in the number of DNA copies are very common in tumor cells and may have a very important role in cancer development and progression. New array platforms provide means ...
Roger Pique-Regi, En-Shuo Tsau, Antonio Ortega, Ro...
126
Voted
BMCBI
2010
156views more  BMCBI 2010»
15 years 3 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
132
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BMCBI
2005
121views more  BMCBI 2005»
15 years 3 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
143
Voted
BMCBI
2007
164views more  BMCBI 2007»
15 years 3 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason