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» Models and Methods in Comparative Genomics
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144
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BMCBI
2006
160views more  BMCBI 2006»
15 years 3 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
121
Voted
BMCBI
2010
107views more  BMCBI 2010»
15 years 3 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
110
Voted
WSC
2004
15 years 4 months ago
Evaluation of Methods Used to Detect Warm-Up Period in Steady State Simulation
This paper reviews the performance of various methods used to detect the warm up length in steady state discrete event simulation. An evaluation procedure is used to compare the m...
Prasad S. Mahajan, Ricki G. Ingalls
143
Voted
BMCBI
2006
143views more  BMCBI 2006»
15 years 3 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
136
Voted
BMCBI
2007
96views more  BMCBI 2007»
15 years 3 months ago
Protein subcellular localization prediction based on compartment-specific features and structure conservation
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
Emily Chia-Yu Su, Hua-Sheng Chiu, Allan Lo, Jenn-K...