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BMCBI
2006
116views more  BMCBI 2006»
15 years 7 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi
BMCBI
2006
149views more  BMCBI 2006»
15 years 7 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
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BMCBI
2006
129views more  BMCBI 2006»
15 years 7 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
DM
2006
128views more  DM 2006»
15 years 7 months ago
Non-trivial t-designs without repeated blocks exist for all t
A computer package is being developed at Bayreuth for the generation and investigation of discrete structures. The package is a C and C++ class library of powerful algorithms endow...
Luc Teirlinck
BMCBI
2007
94views more  BMCBI 2007»
15 years 7 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...