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BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2008
97views more  BMCBI 2008»
14 years 12 months ago
A Population Proportion approach for ranking differentially expressed genes
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Mugdha Gadgil
BMCBI
2007
195views more  BMCBI 2007»
14 years 12 months ago
NeuroTerrain - a client-server system for browsing 3D biomedical image data sets
Background: Three dimensional biomedical image sets are becoming ubiquitous, along with the canonical atlases providing the necessary spatial context for analysis. To make full us...
Carl Gustafson, William J. Bug, Jonathan Nissanov
BMCBI
2007
182views more  BMCBI 2007»
14 years 12 months ago
EDISA: extracting biclusters from multiple time-series of gene expression profiles
Background: Cells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consistin...
Jochen Supper, Martin Strauch, Dierk Wanke, Klaus ...
BMCBI
2007
97views more  BMCBI 2007»
14 years 12 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
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