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BMCBI
2010
125views more  BMCBI 2010»
14 years 10 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2010
179views more  BMCBI 2010»
14 years 10 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
CORR
2010
Springer
177views Education» more  CORR 2010»
14 years 10 months ago
Supervised Random Walks: Predicting and Recommending Links in Social Networks
Predicting the occurrence of links is a fundamental problem in networks. In the link prediction problem we are given a snapshot of a network and would like to infer which interact...
Lars Backstrom, Jure Leskovec
BMCBI
2008
108views more  BMCBI 2008»
14 years 10 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...