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» Morphological Analysis by Multiple Sequence Alignment
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TCBB
2008
95views more  TCBB 2008»
14 years 9 months ago
Solving the Problem of Trans-Genomic Query with Alignment Tables
Abstract-- The trans-genomic query (TGQ) problem -- enabling the free query of biological information, even across genomes -- is a central challenge facing bioinformatics. Solution...
Douglas Stott Parker Jr., Ruey-Lung Hsiao, Yi Xing...
BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2010
94views more  BMCBI 2010»
14 years 9 months ago
A comparative study of conservation and variation scores
Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Fredrik Johansson, Hiroyuki Toh
BIB
2007
101views more  BIB 2007»
14 years 9 months ago
Discovering and detecting transposable elements in genome sequences
The contribution of transposable elements (TEs) to genome structure and evolution as well as their impact on genome sequencing, assembly, annotation and alignment has generated in...
Casey M. Bergman, Hadi Quesneville
BMCBI
2004
154views more  BMCBI 2004»
14 years 9 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...