49 search results - page 3 / 10 » Motif Discovery Through Predictive Modeling of Gene Regulati... |
BMCBI
2007
13 years 6 months ago
2007
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
BMCBI
2008
13 years 6 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
BMCBI
2005
13 years 6 months ago
2005
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
BMCBI
2006
13 years 6 months ago
2006
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
JCB
2008
13 years 6 months ago
2008
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...