19 search results - page 2 / 4 » Motifs in regulatory networks and their structural robustnes... |
BMCBI
2006
14 years 11 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
RECOMB
2007
Springer
15 years 12 months ago
2007
Springer
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
97
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BMCBI
2006
14 years 11 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
138
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BMCBI
2005
14 years 11 months ago
2005
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
102
click to vote
BMCBI
2005
14 years 11 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...