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» Multi-Torrent: A Performance Study
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144
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BMCBI
2007
207views more  BMCBI 2007»
15 years 23 days ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2008
167views more  BMCBI 2008»
15 years 23 days ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli
BMCBI
2008
138views more  BMCBI 2008»
15 years 23 days ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
BMCBI
2008
103views more  BMCBI 2008»
15 years 23 days ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
99
Voted
BMCBI
2008
142views more  BMCBI 2008»
15 years 23 days ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...
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